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poison message that wont go away

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1 exchange 2010 env...

i have been getting a message that sits in my poison queue, it is a spam message that is not getting caught by my spam filter..

but it is sitting there non the less, and it is locking up my queue, and locking up my exchange server env.  i have not even been able to restart the exchange env,  i have had to REBOOT this server every day at 6am, go into the queue, and manually remove the messages... error messages are mail submission, and mail transport.

can anyone help?? i would like to sleep past 6 am... :-(


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