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HTTP Error 404

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Hey everyone. I am experiencing an issue on a Cluster of mail servers, both servers are running Server 2008 and Exchange 2010. The issue is that when using the OWA app in office or external, you are able to log in, pull up a the mailbox, but if you try to"click" on anything (mail item, New button, Reply button) a small window pops up and says "Your network connection isn't available. If the problem continues, contact your help-desk with this HTTP Status code: 404. Then I click on close and everything operates as it should until you click another "function" button. 

There are no errors in the error log that relate to what I am seeing, the cluster is a DAG, both servers passed the ExBPA, and the cluster passed all tests. 

I have been scouring this and MSExchange all day looking for a resolution, I have setup new Perf counters, I have verified the virtual directory....I am running out of ideas on this one....

Thanks in advance for any help...

Ryan


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